19-08-2014, 12:14 PM
The use of colloidal drug carriers can fulfill these objectives by providing site specific delivery with optimal release profiles. 5-Fluorouracil is an anticancer drug used widely in the treatment of stomach, liver and other cancers. However, bone marrow suppression and gastrointestinal reactions are its major adverse effects due to nonspecific distribution in the body. Nanoparticles of 5-Fluorouracil was successfully developed so as to improve treatment efficacy and reduce side effects when used in liver cancer.
The use of colloidal drug carriers can fulfill these objectives by providing site specific delivery with optimal release profiles. 5-Fluorouracil is an anticancer drug used widely in the treatment of stomach, liver and other cancers. However, bone marrow suppression and gastrointestinal reactions are its major adverse effects due to nonspecific distribution in the body. Nanoparticles of 5-Fluorouracil was successfully developed so as to improve treatment efficacy and reduce side effects when used in liver cancer.