26-05-2012, 10:34 AM
NANOROBOTIC CHALLENGES IN BIOMEDICAL APPLICATIONS, DESIGNAND CONTROL
NANOROBOTIC CHALLENGES IN BIOMEDICAL.doc (Size: 316.24 KB / Downloads: 52)
ABSTRACT
Ongoing developments in molecular fabrication, computation, sensors and motors will enable the manufacturing of nanorobots - nanoscale biomolecular machine systems. The present work constitutes a novel simulation approach, intended to be a platform for the design and research of nanorobots control. The simulation approach involves a combined and multi-scale view of the scenario. Fluid dynamics numerical simulation is used to construct the nanorobotic environment, and an additional simulation models nanorobot sensing, control and behavior. We discuss some of the most promising possibilities for nanorobotics applications in biomedical problems, paying a special attention to a stenosed coronary artery case.
. INTRODUCTION
This paper describes a study for developing nanorobotics control design to deal with many of the challenging problems in biomedical applications. The problem we consider here is mainly focused on nanomedicine [10], where the biomedical interventions and manipulations are automatically performed by nanorobots. While these nanorobots cannot be fabricated yet, theoretical and simulation studies defining design.
MEDICAL NANOROBOTIC APPLICATIONS
Applications of nanorobots are expected to provide remarkable possibilities. An interesting utilization of nanorobots may be their attachment to transmigrating inflammatory cells or white blood cells, to reach inflamed tissues and assist in their healing process [3]. Nanorobots will be applied in chemotherapy to combat cancer through precise chemical dosage administration, and a similar approach could be taken to enable nanorobots to deliver anti-HIV drugs.
. PROPOSED DESIGN
Nanorobot manufacturing will undoubtedly require development of breakthrough technologies in fabrication, computation, sensing and manipulation. Researching the requirements, anticipated behavior and performance, and design of control strategies will require simulation tools which will both model foreseeable nanoscale technologies, and in turn influence the development of the same technologies. The simulation approach presented in this paper consists of adopting a multi-scale view of the scenario, which is comprised of: macroscale physical morphology and physiological flow patterns, and on the nanoscale, the nanorobot fluid dynamics, orientation and drive mechanisms, sensing and control. Two simulations are used to achieve the most faithful modeling of nanorobots behavior in a real physical context. These simulations (NCD for the micro level, CFD for the macro level) are described in the next paragraphs, starting with assumptions made for the nanorobot simulation.