08-11-2012, 04:13 PM
NANOBIOSENSORS
[attachment=38611]
Abstract
The revolution of nanotechnology in molecular biology gives an
opportunity to detect and manipulate atoms and molecules at the
molecular and cellular level.
Definition of Nanobiosensor
History
Types of Nanobiosensors
Working Principle and Fabrication of Optical and FET Nanobiosensors
Application Areas and Current Research
Future Research
What is a Nanobiosensor?
A biosensor is a measurement system for the detection of an analyte that combines a biological component with a physicochemical detector, and a nanobiosensor is a biosensor that on the nano-scale size
Biosensor Development
1916 First report on the immobilization of proteins: adsorption of invertase on activated charcoal.
1956 Invention of the first oxygen electrode [Leland Clark]
1962 First description of a biosensor: an amperometric enzyme electrode for glucose. [Leland Clark, New York Academy of Sciences Symposium]
1969 First potentiometric biosensor: urease immobilized on an ammonia electrode to detect urea. [Guilbault and Montalvo]
1970 Invention of the Ion-Selective Field-Effect Transistor (ISFET).
1972/5 First commercial biosensor: Yellow Springs Instruments glucose biosensor.
1976 First bedside artificial pancreas [Clemens et al.]
1980 First fiber optic pH sensor for in vivo blood gases.
1982 First fiber optic-based biosensor for glucose
1983 First surface plasmon resonance (SPR) immunosensor.
1987 Launch of the blood glucose biosensor[ MediSense]
Applications of Nanobiosensors
Biological Applications
DNA Sensors; Genetic monitoring, disease
Immunosensors; HIV, Hepatitis,other viral diseas, drug testing, environmental monitoring…
Cell-based Sensors; functional sensors, drug testing…
Point-of-care sensors; blood, urine, electrolytes, gases, steroids,
drugs, hormones, proteins, other…
Bacteria Sensors; (E-coli, streptococcus, other): food industry,
medicine, environmental, other.
Enzyme sensors; diabetics, drug testing, other.
Environmental Applications
Detection of environmental pollution and toxicity
Agricultural monitoring
Ground water screening
Ocean monitoring
[attachment=38611]
Abstract
The revolution of nanotechnology in molecular biology gives an
opportunity to detect and manipulate atoms and molecules at the
molecular and cellular level.
Definition of Nanobiosensor
History
Types of Nanobiosensors
Working Principle and Fabrication of Optical and FET Nanobiosensors
Application Areas and Current Research
Future Research
What is a Nanobiosensor?
A biosensor is a measurement system for the detection of an analyte that combines a biological component with a physicochemical detector, and a nanobiosensor is a biosensor that on the nano-scale size
Biosensor Development
1916 First report on the immobilization of proteins: adsorption of invertase on activated charcoal.
1956 Invention of the first oxygen electrode [Leland Clark]
1962 First description of a biosensor: an amperometric enzyme electrode for glucose. [Leland Clark, New York Academy of Sciences Symposium]
1969 First potentiometric biosensor: urease immobilized on an ammonia electrode to detect urea. [Guilbault and Montalvo]
1970 Invention of the Ion-Selective Field-Effect Transistor (ISFET).
1972/5 First commercial biosensor: Yellow Springs Instruments glucose biosensor.
1976 First bedside artificial pancreas [Clemens et al.]
1980 First fiber optic pH sensor for in vivo blood gases.
1982 First fiber optic-based biosensor for glucose
1983 First surface plasmon resonance (SPR) immunosensor.
1987 Launch of the blood glucose biosensor[ MediSense]
Applications of Nanobiosensors
Biological Applications
DNA Sensors; Genetic monitoring, disease
Immunosensors; HIV, Hepatitis,other viral diseas, drug testing, environmental monitoring…
Cell-based Sensors; functional sensors, drug testing…
Point-of-care sensors; blood, urine, electrolytes, gases, steroids,
drugs, hormones, proteins, other…
Bacteria Sensors; (E-coli, streptococcus, other): food industry,
medicine, environmental, other.
Enzyme sensors; diabetics, drug testing, other.
Environmental Applications
Detection of environmental pollution and toxicity
Agricultural monitoring
Ground water screening
Ocean monitoring