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Industrial Production of Citric Acid

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Application of Citric Acid: (text,p.524)
Acidulant in food, confectionary, and beverage (75%)
Pharmaceutical (10%), e.g. soluble aspirin preparation
- industrial (15%): complexes with metals such as iron and copper to be stabilizer of oil and fats.

Industrial Production of Citric Acid

Microorganism: Aspergillus niger (mainly), Candida yeast (from carbohydrates or n-alkanes)
Citric acid production is mixed growth associated, mainly take place under nitrogen and phosphate limitation after growth has ceased.
Medium requirements for high production
- Carbon source: molasses or sugar solution.
- Na-ferrocyanide is added to reduce Iron (1.3 ppm) and manganese (<0.1ppm).
- High dissolved oxygen concentration
- High sugar concentration
- pH<2
- 30 oC.