19-08-2014, 12:44 PM
BDMS is a solid and a stable and can be considered as off the shelf bromine source for many useful transformations involving bromination or oxidation.
BDMS is a solid and a stable and can be considered as off the shelf bromine source for many useful transformations involving bromination or oxidation. Using a combination of BDMS and NH4SCN two novel thiocyanation methodologies have been developed and these are:
i) Highly regioselective thiocyanation of aromatic and heteroaromatic compounds.
ii) Selective method -thiocyanation of carbonyl and -dicarbonyl compounds.
These methods are mild, clean, and efficient and occur at room temperature